Allergy in infants under 2 yrs and maternal fish oil supplementation during pregnancy and lactation

This double-blinded, randomised, placebo-controlled trial involving 145 women at risk of delivering an allergic infant supplemented one group with 1.6g EPA and 1.1g DHA from the 25th gestational week through to 3.5 months of breastfeeding. While no significant difference in allergic symptoms were found, the cumulative incidence of IgE-associated diseases in the first 2 years of life was found to be statistically lower in the EPA/DHA supplemented group compared to the control group. Further, a dose-dependent response was demonstrated, where mothers and infants with the highest DHA and EPA proportions had a lower prevalence of IgE-associated diseases.

Fish oil is present in PM Procare (Pregnancy & Pregnancy formulation) and )PM BrightKids (for children’s eye, neural and immune health).

Furuhjelm, C., et al., Allergic disease in infants up to 2 years of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation. Pediatr Allergy Immunol, 2011. 22(5): p. 505-14.